Invasive Validation of Arteriograph Estimates of Central
Blood Pressure in Patients With Type 2 Diabetes
Niklas Blach Rossen,1,2 Esben Laugesen,2 Christian Daugaard Peters,3 Eva Ebbehøj,2
Søren Tang Knudsen,2 Per Løgstrup Poulsen,2 Hans Erik Bøtker,4 and Klavs Würgler Hansen1
background
Central blood pressure (BP) has attracted increasing interest because of
a potential superiority over brachial BP in predicting cardiovascular morbidity
and mortality. Several devices estimating central BP noninvasively
are now available. The aim of our study was to determine the validity of
the Arteriograph, a brachial cuff-based, oscillometric device, in patients
with type 2 diabetes.
methods
We measured central BP invasively and compared it with the
Arteriograph-estimated values in 22 type 2 diabetic patients referred to
elective coronary angiography.
results
The difference (invasively measured BP minus Arteriograph-estimated
BP) in central systolic BP (SBP) was 4.4 ± 8.7 mm Hg (P = 0.03). The limits
of agreement were ±17.1 mm Hg.
conclusions
Compared with invasively measured central SBP, we found a systematic
underestimation by the Arteriograph. However, the limits of agreement
were similar to the previous Arteriograph validation study and to the
invasive validation studies of other brachial cuff-based, oscillometric
devices. A limitation in our study was the large number of patients
(n = 14 of 36) in which the Arteriograph was unable to analyze the pressure
curves. In a research setting,

Invasive validation of a new oscillometric device
(Arteriograph) for measuring augmentation index, central
blood pressure and aortic pulse wave velocity
Iva´n G. Horva´ tha, A´ da´m Ne´metha, Zso´ fia Lenkeya, Nicola Alessandrib,
Fabrizio Tufanob, Pa´ l Kisa, Bala´ zs Gasznera and Attila Czira´ kia
Background The importance of measuring aortic
pulse wave velocity (PWVao), aortic augmentation
index (Aix) and central systolic blood pressure
(SBPao) has been shown under different clinical
conditions; however, information on these
parameters is hard to obtain. The aim of this study
was to evaluate the accuracy of a new, easily applicable
oscillometric device (Arteriograph), determining these
parameters simultaneously, against invasive
measurements.
Methods Aortic Aix, SBPao and PWVao were measured
invasively during cardiac catheterization in 16, 55 and
22 cases, respectively, and compared with the values
measured by the Arteriograph.
Results We found strong correlation between the invasively
measured aortic Aix and the oscillometrically measured
brachial Aix on either beat-to-beat or mean value per patient
basis (rU0.9, P<0.001; rU0.94, P<0.001), which allowed
the noninvasive calculation of the aortic Aix without using
generalized transfer function. Similarly strong correlation
(rU0.95, P<0.001) was found between the invasively
measured and the noninvasively calculated central SBPao;
furthermore, the BHS assessment of the paired differences
fulfilled the ‘B’ grading. The PWVao values measured
invasively and by Arteriograph were 9.41W1.8 m/s and
9.46W1.8 m/s, respectively (meanWSD); furthermore, the
Pearson’s correlation was 0.91 (P<0.001). The limits of